Overview:
Disintegration Testing evaluates how quickly a solid oral dosage form, such as a tablet or capsule, breaks down into smaller particles when placed in a specific fluid medium. This test is essential for confirming that the drug will release its active ingredients efficiently upon ingestion, enabling proper absorption in the body.

Test Description:
The dosage form is placed in a disintegration test apparatus containing a prescribed liquid (typically water, simulated gastric, or intestinal fluid) and maintained at body temperature (37°C ± 2°C). The test measures the time it takes for the sample to fully disintegrate without leaving a palpable core.

Purpose & Benefits:

• Confirms bioavailability readiness by ensuring breakdown before dissolution
• Assesses product performance during quality control and batch release
• Required for regulatory compliance and method validation
• Helps detect formulation defects or changes in manufacturing

Industries Served:

• Pharmaceutical Manufacturers
• Generic Drug Developers
• Nutraceuticals and Dietary Supplements
• Clinical Trial Material Providers